Renal anemia (RA) is a common complication associated with chronic kidney diseases. Its pathological mechanism is attributed to the combined effects of insufficient production of erythropoietin by the ...

Our work provides insights into how cells solve the problem of trafficking a toxic metal, nickel, to the active site of urease. Colonization of Helicobacter pylori in acidic human stomach requires the ...

Nearly all organisms have intimate relationships with communities of microorganisms called the microbiota that are essential for mutual health. However, the microbiota may have life history traits and ...

Catalytic enzymes exhibiting enhanced motion have drawn extensive attention over the past decade; nevertheless, little is known about the effect on the environment induced by enzymes. Herein, we ...

Soil microbial carbon utilization efficiency (CUE) is the efficiency with which microorganisms convert absorbed carbon (C) into their own biomass C, also referred to as microorganism growth efficiency ...

Pogostemon cablin is a traditional Chinese medicine (TCM) that is frequently used to treat various gastrointestinal diseases. Patchouli alcohol (PA), a compound extracted from the Pogostemon cablin, ...

Metallodrugs have been widely used as diagnostic and therapeutic agents. Understanding their mechanisms of action may lead to advances in rational drug design. However, to achieve this, diversified ...

Drug resistance of bacterial pathogens is a growing problem that can be addressed through the discovery of compounds with novel mechanisms of antibacterial activity. Natural products, including plant ...

Figure 1. Role of indoxyl sulfate in the pathogenesis of various forms of cardiovascular disease in chronic kidney disease. EPC indicates endothelial progenitor cell; VSMC, vascular smooth muscle cell ...

Surface-bound enzymes act as pumps in the presence of their specific substrates or promoters, thereby combining sensing and fluidic pumping into a single self-powered microdevice. Using a combination ...